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Cold Urticaria Activity Score (ColdUAS)

Cold Urticaria Activity Score (ColdUAS)

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The Cold Urticaria Activity Score (ColdUAS) is the first instrument for assessing disease activity in patients with cold urticaria (ColdU). The questionnaire is simple and user-friendly, designed for adults and adolescents 12 years and older.

The ColdUAS was developed by a team of urticaria experts at Charité University, led by PD Dr. Dorothea Terhorst-Molawi, PD Dr. Karsten Weller and Prof Dr. Marcus Maurer.

The development process included a literature research, expert reviews as well as interviews with cold urticaria patients by following international guidelines. Possible bias and cofounding factors were discussed and examined during development process. By using an impact analysis and performing cognitive debriefing a final item set consisting of 4 items was generated and tested for reliability and validity. These 4 items are completed daily over a period of 7 days. Validation process is on-going and will be finalized soon.

Quick Facts:
Number of items: 4
Suited for: ≥12 years with cold urticaria
Recall period: porspective, 7 days
Scoring: Easy sum scoring, scoring template available
Copyright: Moxie GmbH (
Terms of use: Free for routine clinical use and non-commercial research, small fee for use in clinical trials/commercial research

Ahsan DM, Altrichter S, Gutsche A, Bernstein JA, Altunergil T, Brockstaedt M, Maurer M, Weller K, Terhorst-Molawi D. Development of the Cold Urticaria Activity Score. Allergy 2022; 77: 2509-2519.


Commercial or non-commercial

If you are interested or on request, we will be happy to send you our PROMs (Patient Reported Outcomes Measures) on the various topics by e-mail. 

Please understand that we have to charge a fee of 15 Euro per PRO when using our PROMs for commercial purposes. Commercial use include, for example, use in industry-sponsored studies, market research and similar purposes.

By non-commercial use we mean e.g. use for consultation hours in hospitals and private practices, use within scientific studies without sponsoring. The prerequisite is that no commercial interest is pursued.

Frequently Asked Questions

Why are there PRO (Patient Reported Outcomes) products that cost nothing and others that cost 15 Euros?

If you plan to use PRO (Patient Reported Outcomes) products (e.g. AAS, AE-QoL, UCT) commercially, there is a small fee per patient (15 €). This applies, for example, to industry-sponsored trials and clinical studies or market research.
You can order free versions, if you plan to use them for non commercial purposes, e.g. for patient management or for academia-driven non commercial
research projects. When you order PRO (Patient Reported Outcomes) products, these instruments are sent per e-mail.

I would like to use PRO (Patient Reported Outcomes) products commercially. Do I have to buy one version each for every time I plan to use it, even in the same patient?

No. Each PRO (Patient Reported Outcomes) products you purchase can be used multiple time by the same patient.

What do I do if PRO (Patient Reported Outcomes) products are not available for my country or in the language I need?

The version you are looking for is probably already under development. Feel free to get in touch with us by e-mail to check when it will be available.