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Cholinergic Urticaria Activity Score (CholUAS)

Cholinergic Urticaria Activity Score (CholUAS)

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The CholUAS is a disease-specific questionnaire to assess the disease activity in patients with cholinergic urticaria. It consists of a daily three-item questionnaire plus one global question and is quick and easy to use for patients.

The CholUAS was developed at the Charité by a team headed by Sabine Altrichter, Karsten Weller and Marcus Maurer. The questions included in the CholUAS were created together with patients. The making of the CholUAS also involved impact and factor analyses as well as visual validity testing, and the development of a scoring system. The CholUAS is also suitable for the use in patient care as well as clinical research and studies.

Quick Facts CholUAS:
Number of items: 3+1
Suited for: All adult (18 years old) patients with cholinergic urticaria
Assessment: Prospectively, every day
Scoring: average weekly score calculation (scoring template available)
Copyright: Moxie GmbH (
Terms of use: Free for routine clinical use and non-commercial research, small fee for use in clinical trials/commercial research

Koch K, Weller K, Werner A, Maurer M, Altrichter S. Antihistamine updosing reduces disease activity in patients with difficult-to-treat cholinergic urticaria. J Allergy Clin Immunol. 2016 Nov;138(5):1483-1485.e9. doi: 10.1016/j.jaci.2016.05.026. 

Schnarkowski P, Salameh P, Grekowitz E., Terhorst E, Maurer M, Weller K, Altrichter S, Validation of the cholinergic urticaria activity score, CholUAS, submitted for publication 01/2024

Commercial or non-commercial

If you are interested or on request, we will be happy to send you our PROMs (Patient Reported Outcomes Measures) on the various topics by e-mail. 

Please understand that we have to charge a fee of 15 Euro per PRO when using our PROMs for commercial purposes. Commercial use include, for example, use in industry-sponsored studies, market research and similar purposes.

By non-commercial use we mean e.g. use for consultation hours in hospitals and private practices, use within scientific studies without sponsoring. The prerequisite is that no commercial interest is pursued.

Frequently Asked Questions

Why are there PRO (Patient Reported Outcomes) products that cost nothing and others that cost 15 Euros?

If you plan to use PRO (Patient Reported Outcomes) products (e.g. AAS, AE-QoL, UCT) commercially, there is a small fee per patient (15 €). This applies, for example, to industry-sponsored trials and clinical studies or market research.
You can order free versions, if you plan to use them for non commercial purposes, e.g. for patient management or for academia-driven non commercial
research projects. When you order PRO (Patient Reported Outcomes) products, these instruments are sent per e-mail.

I would like to use PRO (Patient Reported Outcomes) products commercially. Do I have to buy one version each for every time I plan to use it, even in the same patient?

No. Each PRO (Patient Reported Outcomes) products you purchase can be used multiple time by the same patient.

What do I do if PRO (Patient Reported Outcomes) products are not available for my country or in the language I need?

The version you are looking for is probably already under development. Feel free to get in touch with us by e-mail to check when it will be available.