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Cholinergic Urticaria Quality of Life Questionnaire (CholU-QoL)

Cholinergic Urticaria Quality of Life Questionnaire (CholU-QoL)

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The Quality of Life Questionnaire for Patients with Cholinergic Urticaria (CholU-QoL) is the first and only available quality of life questionnaire specifically designed for patients with cholinergic urticaria. CholU-QoL is easy to use and has been validated specifically for patients with cholinergic urticaria.

The CholU-QoL was developed at the Charité by a team headed by Dr. Sabine Altrichter, PD Dr. Karsten Weller and Prof. Marcus Maurer. Initially, 96 questions were created using established procedures and in accordance with international recommendations. Using impact and factor analyses as well as visual validity testing, 28 of these questions were selected for the final CholU-QoL instrument. This instrument was then checked for validity and reliability and examined with regard to possible influencing factors.

Quick Facts CholU-QoL:
Number of items: 28
Recall period: 2 weeks
Suited for: All adult (≥18 years old) patients with cholinergic urticaria                                     
Copyright: Moxie GmbH (
Terms of use: Free for routine clinical use and non-commercial research, small fee for use in clinical trials/commercial research

Ruft J, Asady A, Staubach P, Casale T, Sussmann G, Zuberbier T, Maurer M, Weller K, Altrichter S. Development and validation of the Cholinergic Urticaria Quality-of-Life Questionnaire (CholU-QoL). Clin Exp Allergy. 2018 Apr;48(4):433-444. doi: 10.1111/cea.13102. Epub 2018 Feb 28.

Altrichter S, Mellerowicz E, Terhorst-Molawi D, Grekowitz E, Weller K, Maurer M. Disease Impact, Diagnostic Delay, and Unmet Medical Needs of Patients With Cholinergic Urticaria in German-Speaking Countries. Front Allergy. 2022 May 25;3:867227. doi: 10.3389/falgy.2022.867227.

Commercial or non-commercial

If you are interested or on request, we will be happy to send you our PROMs (Patient Reported Outcomes Measures) on the various topics by e-mail. 

Please understand that we have to charge a fee of 15 Euro per PRO when using our PROMs for commercial purposes. Commercial use include, for example, use in industry-sponsored studies, market research and similar purposes.

By non-commercial use we mean e.g. use for consultation hours in hospitals and private practices, use within scientific studies without sponsoring. The prerequisite is that no commercial interest is pursued.

Frequently Asked Questions

Why are there PRO (Patient Reported Outcomes) products that cost nothing and others that cost 15 Euros?

If you plan to use PRO (Patient Reported Outcomes) products (e.g. AAS, AE-QoL, UCT) commercially, there is a small fee per patient (15 €). This applies, for example, to industry-sponsored trials and clinical studies or market research.
You can order free versions, if you plan to use them for non commercial purposes, e.g. for patient management or for academia-driven non commercial
research projects. When you order PRO (Patient Reported Outcomes) products, these instruments are sent per e-mail.

I would like to use PRO (Patient Reported Outcomes) products commercially. Do I have to buy one version each for every time I plan to use it, even in the same patient?

No. Each PRO (Patient Reported Outcomes) products you purchase can be used multiple time by the same patient.

What do I do if PRO (Patient Reported Outcomes) products are not available for my country or in the language I need?

The version you are looking for is probably already under development. Feel free to get in touch with us by e-mail to check when it will be available.