{"title":"Angioedema","description":"Angioedema is swelling caused by increased permeability of the blood vessels in the deeper layers of the skin or mucous membrane. These swellings can occur in various parts of the body, such as the lips or tongue. The causes of angioedema are varied and angioedema is often recurrent.","products":[{"product_id":"aas","title":"Angioedema Activity Score (AAS)","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eThe Angioedema Activity Score (AAS) is a validated, easy to use questionnaire to determine disease activity in patients with recurrent angioedema. It can be used in patients with histamine-mediated, bradykinin-mediated and idiopathic recurrent angioedema. The AAS is designed as a diary-type tool, to be used by patients for a daily documentation of their swelling episodes, including their duration, severity and impact on daily functioning and appearance.\u003c\/p\u003e\n\u003cp\u003eThe AAS was developed by a Charité team of scientists led by Dr. Karsten Weller and Dr. Marcus Maurer. Briefly, after a set of potential AAS items was developed, item evaluation and reduction were performed, for example, by means of impact analysis and by checking for face validity. In addition, the items of the final AAS were tested for their validity and reliability during a validation study.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuick Facts AAS:\u003cbr\u003e\u003c\/strong\u003eNumber of items: 6 (on days with angioedema), 1 (on days without)\u003cbr\u003eSuited for: Adults (≥18 years old) with histamine-mediated, bradykinin-mediated and idiopathic recurrent angioedema.\u003cbr\u003eAssessment: prospectively, e.g. 4 weeks\u003cbr\u003eScoring: sum scoring, scoring template available\u003cbr\u003eCopyright: Moxie GmbH (www.moxie-gmbh.de)\u003cbr\u003eTerms of use: Free for routine clinical use and non commercial research, small fee for use in clinical trials\/commercial research\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReference\u003c\/strong\u003e:\u003cbr\u003eWeller K, Groffik A, Magerl M, Tohme N, Martus P, Krause K, Metz M, Staubach P, Maurer M. Development, validation, and initial results of the Angioedema Activity Score. Allergy 2013; DOI: 10.1111\/all.12209.\u003c\/p\u003e","brand":"MOXIE","offers":[{"title":"Default Title","offer_id":47516494102866,"sku":"","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/7351\/7650\/files\/AngioedemaActivityScore_AAS.png?v=1704968978"},{"product_id":"aect","title":"Angioedema Control Test 3 Month recall period (AECT3)","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eThe Angioedema Control Test (AECT) is a validated, easy to use questionnaire to determine disease control in patients with recurrent angioedema. It can be used in patients with histamine-mediated, bradykinin-mediated and idiopathic recurrent angioedema. The AECT is designed as a retrospective instrument and may be applied and evaluated quickly and easily during patient consultations.\u003c\/p\u003e\n\u003cp\u003eThe AECT was developed by a Charité team of scientists led by Dr. Karsten Weller and Dr. Marcus Maurer. Briefly, after a set of potential AECT items was developed, item evaluation and reduction were performed, for example, by means of impact analysis and by checking for face validity. In addition, the items of the final AECT were tested for their validity and reliability during a validation study.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eQuick Facts AECT:\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eNumber of items: 4\u003cbr data-mce-fragment=\"1\"\u003eSuited for: Adults (≥18 years old) with histamine-mediated, bradykinin-mediated and idiopathic recurrent angioedema\u003cbr\u003eAssessment: retrospectively (recall period: 3 months)\u003cbr\u003eScoring: easy sum scoring, scoring template available \u003cbr data-mce-fragment=\"1\"\u003eCutoff value: 10 points (\u0026lt;10 points corresponds to poorly controlled disease)\u003cbr data-mce-fragment=\"1\"\u003eCopyright: Moxie GmbH (\u003ca href=\"https:\/\/moxie-gmbh.de\/\" data-mce-fragment=\"1\" data-mce-href=\"https:\/\/moxie-gmbh.de\/\"\u003ewww.moxie-gmbh.de)\u003c\/a\u003e\u003cbr\u003eTerms of use: Free for routine clinical use and non-commercial research, fee for use in clinical trials\/commercial research\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e:\u003cbr data-mce-fragment=\"1\"\u003eWeller K, Donoso T, Magerl M, Aygören-Pürsün E, Staubach P, Martinez-Saguer I, Hawro T, Altrichter S, Krause K, Siebenhaar F, Metz M, Zuberbier T, Freier D, Maurer M. Validation of the Angioedema Control Test (AECT) - A Patient-Reported Outcome Instrument for Assessing Angioedema Control. J Allergy Clin Immunol Pract. 2020, doi: 10,1016\/y.jaip.2020.02.038. \u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eWeller K, Donoso T, Magerl M, Aygören-Pürsün E, Staubach P, Martinez-Saguer I, Hawro T, Altrichter S, Krause K, Siebenhaar F, Metz M, Zuberbier T, Freier D, Maurer M. Development of the Angioedema Control Test - A patient-reported outcome measure that assesses disease control in patients with recurrent angioedema. Allergy. 2019, doi: 10.1111\/all.14144.\u003c\/p\u003e","brand":"MOXIE","offers":[{"title":"Default Title","offer_id":47520502612306,"sku":"","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/7351\/7650\/files\/AngioedemaControlTest_AECT.png?v=1704968969"},{"product_id":"ae-qol","title":"Angioedema Quality of Life Questionnaire (AE-QoL)","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cdiv class=\"content--title\" data-mce-fragment=\"1\"\u003e\n\u003cp\u003eThe Angioedema Quality of Life Questionnaire (AE-QoL) is a validated, easy to use questionnaire to determine health-related quality of life in patients with recurrent angioedema. It can be used in patients with histamine-mediated, bradykinin-mediated and idiopathic recurrent angioedema.\u003c\/p\u003e\n\u003cp\u003eThe AE-QoL was developed by a Charité team of scientists led by Dr. Karsten Weller and Dr. Marcus Maurer. Briefly, after a set of potential AE-QoL items was developed, item evaluation and reduction were performed, for example, by means of impact analysis and by checking for face validity. In addition, the final 17-items were tested for their validity and reliability during a validation study.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product--description\" data-mce-fragment=\"1\" itemprop=\"description\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eQuick Facts AE-QoL:\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eNumber of items: 17\u003cbr\u003eSuited for:  All Adults (≥18 years old) with recurrent angioedema\u003cbr data-mce-fragment=\"1\"\u003eRecall period: 4 weeks\u003cbr data-mce-fragment=\"1\"\u003eAssessment: retrospectively (recall period: 4 weeks)\u003cbr\u003eDomains:  Functioning, Fatigue\/Mood, Fears\/Shame, Food\u003cbr data-mce-fragment=\"1\"\u003eScoring: Domain scores and total score (0-100 points each), scoring template available\u003cbr\u003eCopyright: Moxie GmbH (www.moxie-gmbh.de)\u003cbr data-mce-fragment=\"1\"\u003eTerms of use: Free for routine clinical use and non commercial research, small fee for use in clinical trials\/commercial research\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong\u003eReference\u003c\/strong\u003e:\u003cbr\u003eWeller K, Groffik A, Magerl M, Tohme N, Martus P, Krause K, Metz M, Staubach P, Maurer M. Development and construct validation of the angioedema quality of life questionnaire. Allergy 2012; 67: 1289–1298.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"MOXIE","offers":[{"title":"Default Title","offer_id":47540150829394,"sku":"","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/7351\/7650\/files\/AngioedemaQualityofLifeQuestionnaire_AE-QoL.png?v=1704968960"},{"product_id":"angioedema-control-test-4-week-aect4","title":"Angioedema Control Test 4 Weeks recall period (AECT4)","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eThe Angioedema Control Test (AECT) is a validated, easy to use questionnaire to determine disease control in patients with recurrent angioedema. It can be used in patients with histamine-mediated, bradykinin-mediated and idiopathic recurrent angioedema. The AECT is designed as a retrospective instrument and may be applied and evaluated quickly and easily during patient consultations.\u003c\/p\u003e\n\u003cp\u003eThe AECT was developed by a Charité team of scientists led by Dr. Karsten Weller and Dr. Marcus Maurer. Briefly, after a set of potential AECT items was developed, item evaluation and reduction were performed, for example, by means of impact analysis and by checking for face validity. In addition, the items of the final AECT were tested for their validity and reliability during a validation study.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eQuick Facts AECT:\u003cbr\u003e\u003c\/strong\u003eNumber of items: 4\u003cbr\u003eSuited for: Adults (≥18 years old) with histamine-mediated, bradykinin-mediated and idiopathic recurrent angioedema.\u003cbr\u003eAssessment: retrospectively (recall period: 4 weeks)\u003cbr\u003eScoring: easy sum scoring, scoring template available\u003cbr\u003eCutoff-value: 10 points (\u0026lt;10 points indicate poorly controlled recurrent angioedema)\u003cbr\u003eCopyright: Moxie GmbH (\u003ca href=\"http:\/\/www.moxie-gmbh.de\"\u003ewww.moxie-gmbh.de\u003c\/a\u003e)\u003cbr\u003eTerms of use: Free for routine clinical use and non-commercial research, fee for use in clinical trials\/commercial research\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e:\u003cbr data-mce-fragment=\"1\"\u003eWeller K, Donoso T, Magerl M, Aygören-Pürsün E, Staubach P, Martinez-Saguer I, Hawro T, Altrichter S, Krause K, Siebenhaar F, Metz M, Zuberbier T, Freier D, Maurer M. Validation of the Angioedema Control Test (AECT) - A Patient-Reported Outcome Instrument for Assessing Angioedema Control. J Allergy Clin Immunol Pract. 2020, doi: 10,1016\/y.jaip.2020.02.038. \u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eWeller K, Donoso T, Magerl M, Aygören-Pürsün E, Staubach P, Martinez-Saguer I, Hawro T, Altrichter S, Krause K, Siebenhaar F, Metz M, Zuberbier T, Freier D, Maurer M. Development of the Angioedema Control Test - A patient-reported outcome measure that assesses disease control in patients with recurrent angioedema. Allergy. 2019, doi: 10.1111\/all.14144.\u003c\/p\u003e","brand":"MOXIE","offers":[{"title":"Default Title","offer_id":47625803858258,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/7351\/7650\/files\/AngioedemaControlTest_AECT_18207c3a-5b6e-4c21-8aaf-d84d44e0b476.png?v=1706530376"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/7351\/7650\/collections\/Angioedema.png?v=1706276370","url":"https:\/\/moxie-gmbh.de\/collections\/angioedema.oembed","provider":"MOXIE","version":"1.0","type":"link"}